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CSK antibody

KO/KD
Anti-CSK antibody used in Western Blot (WB). GTX35201
Anti-CSK antibody used in Western Blot (WB). GTX35201
Anti-CSK antibody used in IHC (Paraffin sections) (IHC-P). GTX35201
Anti-CSK antibody used in IHC (Paraffin sections) (IHC-P). GTX35201
Anti-CSK antibody used in Western Blot (WB). GTX35201
Anti-CSK antibody used in IHC (Paraffin sections) (IHC-P). GTX35201

Cat. No. GTX35201

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all CSK products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CSK (NP_001120662.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-terminal Src kinase

Cellular Localization

Cytoplasm,Cell membrane

Background

The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-CSK antibody used in Western Blot (WB). GTX35201

GTX35201 WB Image

KO/KD

WB analysis of normal (control) and knockout (KO) 293T cell lysate using GTX35201 CSK antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-CSK antibody used in Western Blot (WB). GTX35201

GTX35201 WB Image

WB analysis of various sample lysates using GTX35201 CSK antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-CSK antibody used in IHC (Paraffin sections) (IHC-P). GTX35201

GTX35201 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX35201 CSK antibody.
Dilution : 1:100

Anti-CSK antibody used in IHC (Paraffin sections) (IHC-P). GTX35201

GTX35201 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX35201 CSK antibody.
Dilution : 1:100

Anti-CSK antibody used in Western Blot (WB). GTX35201

GTX35201 WB Image

WB analysis of various sample lysates using GTX35201 CSK antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-CSK antibody used in IHC (Paraffin sections) (IHC-P). GTX35201

GTX35201 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX35201 CSK antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399