APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 - 2 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Colon Tissue Lysate(GTX27928)
Product Note
GJB2 antibody is human specific.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Connexin 26 antibody was raised against a 16 amino acid peptide near the center of human Connexin 26.The immunogen is located within amino acids 80 - 130 of Connexin 26.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
gap junction protein beta 2 , CX26 , DFNA3 , DFNA3A , DFNB1 , DFNB1A , HID , KID , NSRD1 , PPK
Cellular Localization
Cell membrane; Multi-pass membrane protein
Background
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq, Oct 2008]
Database
Research Area
DATA IMAGES
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GTX17229 WB Image
WB analysis of human colon tissue lysate using GTX17229 Connexin 26 antibody. Working concentration : (A) 1 and (B) 2 μg/ml
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REFERENCE
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REVIEW
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