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DNMT1 antibody

Anti-DNMT1 antibody used in Immunoprecipitation (IP). GTX11891
Anti-DNMT1 antibody used in Western Blot (WB). GTX11891
Anti-DNMT1 antibody used in Proximity ligation assay (PLA). GTX11891

Cat. No. GTX11891

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IP, PLA

Reactivity

 Human, Mouse
Package
50 μg ($399)
See all DNMT1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:100 - 1:2000
IP 1:10 - 1:500
PLA Assay dependent
Not tested in other applications.

Calculated MW

183 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris-Citrate/Phosphate

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The immunogen recognized by this antibody maps to a region between residue 700 and 750 of human DNA-Methyltranserase 1 using the numbering given in entry NP_001370.1 (GeneID 1786).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

DNA methyltransferase 1 , ADCADN , AIM , CXXC9 , DNMT , HSN1E , MCMT , m.HsaI

Cellular Localization

Nucleus

Background

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-DNMT1 antibody used in Immunoprecipitation (IP). GTX11891

GTX11891 IP Image

(A)WB analysis of HeLa nuclear extracts using GTX11891 DNMT1 antibody.
Loading amount : 50μg
(B)IP analysis of HeLa nuclear extracts using GTX11891 DNMT1 antibody.
Dilution : 0.2 μg/ml

Anti-DNMT1 antibody used in Western Blot (WB). GTX11891

GTX11891 WB Image

WB analysis of HeLa and 293T cell lysate using GTX11891 DNMT1 antibody.
Dilution : 1 μg/ml

Anti-DNMT1 antibody used in Proximity ligation assay (PLA). GTX11891

GTX11891 PLA Image

PLA analysis of MCF-7 cells using GTX11891 DNMT1 antibody and anti-human USP7 antibody.
Green : Actin
Red : positive signal
Blue : DAPI

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399