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Daxx antibody [7A11]

Anti-Daxx antibody [7A11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83312
Anti-Daxx antibody [7A11] used in Western Blot (WB). GTX83312
Anti-Daxx antibody [7A11] used in Flow cytometry (FACS). GTX83312
Anti-Daxx antibody [7A11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83312

Cat. No. GTX83312

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7A11

Isotype

 IgG1

Application

 WB, ICC/IF, FACS, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all Daxx products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ICC/IF 1/200 - 1/1000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

81 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human DAXX expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

death domain associated protein , BING2 , DAP6 , EAP1 , SMIM40

Cellular Localization

Cytoplasm,nucleoplasm,Nucleolus

Background

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]

Database

Research Area

DATA IMAGES

Anti-Daxx antibody [7A11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83312

GTX83312 ICC/IF Image

ICC/IF analysis of PANC-1 cells using GTX83312 Daxx antibody [7A11].
Green : Daxx
Blue: DRAQ5 fluorescent DNA dye

Anti-Daxx antibody [7A11] used in Western Blot (WB). GTX83312

GTX83312 WB Image

WB analysis of K562 cell lysate (1) using GTX83312 Daxx antibody [7A11].

Anti-Daxx antibody [7A11] used in Flow cytometry (FACS). GTX83312

GTX83312 FACS Image

FACS analysis of HeLa cells using GTX83312 Daxx antibody [7A11].
Green : Daxx
Purple : negative control

Anti-Daxx antibody [7A11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83312

GTX83312 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX83312 Daxx antibody [7A11].
Green : Daxx
Blue: DRAQ5 fluorescent DNA dye
Red : Actin filaments

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399