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Desmoglein 2 antibody [6D8]

Cat. No. GTX12078

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6D8

Isotype

 IgG1

Application

 WB, ICC/IF, IP

Reactivity

 Human
Package
50 μg ($399)
See all Desmoglein 2 products

APPLICATION

Application Note

IF: Use at a dilution of 1/10. IP: Use at an assay dependent dilution. WB: Use at a dilution of 1/10. Predicted molecular weight: 165 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

122 kDa. ( Note )

Positive Control

Colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.

Product Note

GTX12078 reacts with Desmoglein 2. Does not cross-react with Desmoglein 1 or Desmoglein 3.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Unfortunately, this information is considered to be commercially sensitive

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

desmoglein 2 , CDHF5 , HDGC

Cellular Localization

Cell membrane; Single-pass type I membrane protein

Background

This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399