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Endothelin B Receptor antibody [HL2918]

Recombinant antibody Orthogonal
Anti-Endothelin B Receptor antibody [HL2918] used in Western Blot (WB). GTX640261
Anti-Endothelin B Receptor antibody [HL2918] used in Western Blot (WB). GTX640261
Anti-Endothelin B Receptor antibody [HL2918] used in Western Blot (WB). GTX640261
Anti-Endothelin B Receptor antibody [HL2918] used in IHC (Paraffin sections) (IHC-P). GTX640261

Cat. No. GTX640261

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL2918

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all Endothelin B Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

49 kDa. ( Note )

Product Note

This antibody was raised against rat Endothelin B Receptor Intracellular domain.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No Preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Synthetic peptide encompassing a sequence within the Intracellular domain of rat Endothelin B Receptor. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

endothelin receptor type B , Ednra , Etb

Cellular Localization

Cell membrane

Background

Enables endothelin receptor activity and type 1 angiotensin receptor binding activity. Involved in several processes, including blood vessel diameter maintenance; positive regulation of penile erection; and positive regulation of renal sodium excretion. Located in membrane raft; nuclear membrane; and plasma membrane. Used to study several diseases, including artery disease (multiple); lymphopenia; megacolon (multiple); portal hypertension; and type 2 diabetes mellitus. Biomarker of asthma; hepatopulmonary syndrome; and hypertension. Human ortholog(s) of this gene implicated in ABCD syndrome; Hirschsprung's disease; Waardenburg syndrome type 4A; Waardenburg's syndrome; and asthma. Orthologous to human EDNRB (endothelin receptor type B). [provided by Alliance of Genome Resources, Apr 2022]

Database

Research Area

DATA IMAGES

Anti-Endothelin B Receptor antibody [HL2918] used in Western Blot (WB). GTX640261

GTX640261 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Endothelin B Receptor antibody [HL2918] (GTX640261) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Endothelin B Receptor antibody [HL2918] used in Western Blot (WB). GTX640261

GTX640261 WB Image

Various tissue extracts (50 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Endothelin B Receptor antibody [HL2918] (GTX640261) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Endothelin B Receptor antibody [HL2918] used in Western Blot (WB). GTX640261

GTX640261 WB Image

Orthogonal

Non-transfected (–) and transfected (+) boiled and unboiled 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Endothelin B Receptor antibody [HL2918] (GTX640261) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Endothelin B Receptor antibody [HL2918] used in IHC (Paraffin sections) (IHC-P). GTX640261

GTX640261 IHC-P Image

Endothelin B Receptor antibody [HL2918] detects Endothelin B Receptor protein by immunohistochemical analysis.
Sample: Paraffin-embedded human breast carcinoma.
Endothelin B Receptor stained by Endothelin B Receptor antibody [HL2918] (GTX640261) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

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Package List Price ($)
$ 399
$ 169
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