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FLT3 antibody [7B7C3]

Anti-FLT3 antibody [7B7C3] used in IHC (Paraffin sections) (IHC-P). GTX60777
Anti-FLT3 antibody [7B7C3] used in Western Blot (WB). GTX60777
Anti-FLT3 antibody [7B7C3] used in IHC (Paraffin sections) (IHC-P). GTX60777
Anti-FLT3 antibody [7B7C3] used in ELISA (ELISA). GTX60777

Cat. No. GTX60777

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7B7C3

Isotype

 IgG1

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($409)
See all FLT3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

113 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant fragment of human FLT3 (AA: 930-991) expressed in E. Coli.

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

fms related tyrosine kinase 3 , CD135 , FLK-2 , FLK2 , STK1

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]

Database

Research Area

DATA IMAGES

Anti-FLT3 antibody [7B7C3] used in IHC (Paraffin sections) (IHC-P). GTX60777

GTX60777 IHC-P Image

IHC-P analysis of cervical cancer tissue using GTX60777 FLT3 antibody [7B7C3].

Anti-FLT3 antibody [7B7C3] used in Western Blot (WB). GTX60777

GTX60777 WB Image

WB analysis of human FLT3 recombinant protein using GTX60777 FLT3 antibody [7B7C3].

Anti-FLT3 antibody [7B7C3] used in IHC (Paraffin sections) (IHC-P). GTX60777

GTX60777 IHC-P Image

IHC-P analysis of liver cancer tissue using GTX60777 FLT3 antibody [7B7C3].

Anti-FLT3 antibody [7B7C3] used in ELISA (ELISA). GTX60777

GTX60777 ELISA Image

ELISA analysis of antigen using GTX60777 FLT3 antibody [7B7C3].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409