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HLA-B7 antibody [BB7.1]

Anti-HLA-B7 antibody [BB7.1] used in Flow cytometry (FACS). GTX639674
Anti-HLA-B7 antibody [BB7.1] used in Flow cytometry (FACS). GTX639674

Cat. No. GTX639674

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 BB7.1

Isotype

 IgG1

Application

 FACS

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all HLA-B7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 1:50-1:200
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The immunogen used to generate this antibody corresponds to human HLA-B7.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

major histocompatibility complex, class I, B , AS , B-4901 , HLAB

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-HLA-B7 antibody [BB7.1] used in Flow cytometry (FACS). GTX639674

GTX639674 FACS Image

HLA-B7 antibody [BB7.1] (GTX639674) detects HLA-B7 protein by flow cytometry analysis. Sample: non-fixed and non-permeabilized PBMC; gated on granulocytes.
Black: Unlabelled sample was used as a control.
Red: HLA-B7 antibody [BB7.1] (GTX639674) dilution: 1:50.
Acquisition of 20,000 events were collected using a Alexa Flour 488-conjugated secondary antibody for FACS analysis.

Anti-HLA-B7 antibody [BB7.1] used in Flow cytometry (FACS). GTX639674

GTX639674 FACS Image

HLA-B7 antibody [BB7.1] (GTX639674) detects HLA-B7 protein by flow cytometry analysis. Sample: non-fixed and non-permeabilized PBMC; gated on monocytes.
Black: Unlabelled sample was used as a control.
Red: HLA-B7 antibody [BB7.1] (GTX639674) dilution: 1:50.
Acquisition of 20,000 events were collected using a Alexa Flour 488-conjugated secondary antibody for FACS analysis.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
Custom Conjugations