Summary
C-reactive protein, also known as PTX1, is a member of the pentraxin family and is involved in complement activation and regulation. C-reactive proteins are found as non-covalently associated globular subunits of the serum-soluble cyclic pentameric complex. This recombinant human C- reactive protein corresponds to the 27.75 kDa (224 a.a.) isoform 1 with an intrachain disulfide bond and no glycosylation modification (RefSeq: NP_000558.2; UniProt ID: P02741). It is His-tagged at the C-terminus.
Form
Lyophilized powder
Buffer
Reconstitute with distilled water to 0.4 mg/ml. Lyophilized from PBS, 2% Trehalose, 5% Mannitol, 0.01% Tween-80.
Preservative
No Preservative
Storage
Store at 4ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. For long-term storage after reconstitution, aliquot and store at -70ºC or below. Do not vortex.
Region/Sequence
C-terminal His tagged full-length Humans CRP protein (1-224aa of AAL48218.2)
Expression System
HEK293 cells
Purity
>95%
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
C-reactive protein , PTX1
Cellular Localization
Secreted
Background
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
Database
Research Area