APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.2-2.5 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
293T , kidney , lung , mouse heart , spleen , thymus
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to an Internal region of Human NFKBIA
Purification
Affinity Purified
Conjugation
Unconjugated
RRID
AB_424685
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
NFKB inhibitor alpha , EDAID2 , IKBA , MAD-3 , NFKBI
Cellular Localization
Cytoplasm,Nucleus
Background
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
Database
Research Area
DATA IMAGES
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GTX77737 WB Image
WB analysis of mouse heart, kidney, lung, thymus, and spleen tissue using GTX77737 NFKBIA antibody at 1:1000. Loading amount: 100ug.
Lane 1. mouse heart lysate
Lane 2. mouse kidney lysate
Lane 3. mouse lung lysate
Lane 4. mouse thymus lysate
Lane 5. mouse spleen lysate
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GTX77737 WB Image
WB analysis of 293T cells using GTX77737 NFKBIA antibody at 0.2-1μg/ml.
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REFERENCE
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REVIEW
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