GeneTex

  • Country / Location Selection

United States (US)

Kiss1 antibody [HL3043]

Recombinant antibody KO/KD
Anti-Kiss1 antibody [HL3043] used in Western Blot (WB). GTX640486

Cat. No. GTX640486

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL3043

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all Kiss1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

15 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No Preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human Kiss1.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

KiSS-1 metastasis suppressor , HH13 , KiSS-1

Cellular Localization

Secreted

Background

This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012]

Database

Research Area

DATA IMAGES

Anti-Kiss1 antibody [HL3043] used in Western Blot (WB). GTX640486

GTX640486 WB Image

KO/KD

Non-transfected (–) and transfected (+) MDA-MB-231 whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with Kiss1 antibody [HL3043] (GTX640486) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

There are currently no references for Kiss1 antibody [HL3043] (GTX640486). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Kiss1 antibody [HL3043] (GTX640486). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 399
$ 169
Available soon.
Custom Conjugations