GeneTex

  • Country / Location Selection

United States (US)

LARGE (aa421-433) antibody, Internal

Anti-LARGE (aa421-433) antibody, Internal used in Western Blot (WB). GTX88124

Cat. No. GTX88124

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all LARGE products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-3μg/ml
Not tested in other applications.

Calculated MW

88 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88124-PEP).

Predict Reactivity

Bovine, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-SEADVNSENLQKQ, from the internal region of the protein sequence according to NP_004728.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

LARGE xylosyl- and glucuronyltransferase 1 , LARGE , MDC1D , MDDGA6 , MDDGB6

Cellular Localization

Golgi apparatus membrane

Background

This gene encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. The protein encoded by this gene is the glycotransferase that adds the final xylose and glucuronic acid to alpha-dystroglycan and thereby allows alpha-dystroglycan to bind ligands including laminin 211 and neurexin. Mutations in this gene cause several forms of congenital muscular dystrophy characterized by cognitive disability and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2018]

Database

Research Area

DATA IMAGES

Anti-LARGE (aa421-433) antibody, Internal used in Western Blot (WB). GTX88124

GTX88124 WB Image

WB analysis of human kidney lysate using GTX88124 LARGE (aa421-433) antibody, Internal.
Dilution : 1μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

There are currently no references for LARGE (aa421-433) antibody, Internal (GTX88124). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for LARGE (aa421-433) antibody, Internal (GTX88124). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399