APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:400 - 1:800 |
1:50 - 1:200 |
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes human MMP-14 in western blot without cross reactivity with human MMP-1-13, and MMP14-15.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
200 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human recombinant MMP-14
Purification
Protein G purified
From tissue culture supernatant
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
MMP14 , MMPX1 , MT1MMP , MTMMP , MTMMP 1 , MTMMP1 , WNCHRS , matrix metallopeptidase 14
Cellular Localization
Membrane,Melanosome,Cytoplasm
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX52480 IHC-P Image
IHC-P analysis of formalin fixed human placenta tissue using GTX52480 MMP14 antibody [9E10].
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REFERENCE
There are currently no references for MMP14 antibody [9E10] (GTX52480). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for MMP14 antibody [9E10] (GTX52480). Be the first to share your experience with this product.