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MRP4 antibody [M4I-80]

Cat. No. GTX15598

Host

 Rat

Clonality

 Monoclonal

Clone Name

 M4I-80

Isotype

 IgG2a

Application

 WB, ICC/IF, IHC-Fr

Reactivity

 Human, Mouse
Package
100 μg ($509)
See all MRP4 products

APPLICATION

Application Note

ICC: Use at a dilution of 1/20 - 1/50. IHC-Fr: Use at a dilution of 1/20. WB: Use at a dilution of 1/20 - 1/50. Predicted molecular weight: 150 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

150 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant, 0.7% BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fusion protein: AIERVSEAIV SIRRIQTFLL LDEISQRNRQ LPSDGKKMVH VQDFTAFWDK ASETPTLQGL , corresponding to amino acids 372-431 of Human MRP4 and E. coli maltose binding protein.

Purification

Tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ATP binding cassette subfamily C member 4 , MOAT-B , MOATB , MRP4

Cellular Localization

Membrane; Multi-pass membrane protein

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Database

Research Area

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 509