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NALP1 antibody

Anti-NALP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04254
Anti-NALP1 antibody used in Western Blot (WB). GTX04254
Anti-NALP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04254
Anti-NALP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04254
Anti-NALP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04254
Anti-NALP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04254

Cat. No. GTX04254

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Rat
Package
100 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
ICC/IF 1:50-1:200
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

166 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.05% proclin300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1370-1473 of human NLRP1 (NP_127497.1)

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NLR family pyrin domain containing 1 , AIADK , CARD7 , CIDED , CLR17.1 , DEFCAP , DEFCAP-L/S , MSPC , NAC , NALP1 , PP1044 , SLEV1 , VAMAS1

Cellular Localization

Cytoplasm, cytosol , Cytoplasm , Nucleus

Background

This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-NALP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04254

GTX04254 ICC/IF Image

ICC/IF analysis of PC-12 cells using GTX04254 NALP1 antibody.
Dilution : 1:50
Blue : DAPI

Anti-NALP1 antibody used in Western Blot (WB). GTX04254

GTX04254 WB Image

WB analysis of K562 cell lysates using GTX04254 NALP1 antibody.
Loading : 25 μg
Dilution : 1:1000

Anti-NALP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04254

GTX04254 ICC/IF Image

ICC/IF analysis of K562 cells using GTX04254 NALP1 antibody.
Dilution : 1:50
Blue : DAPI

Anti-NALP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04254

GTX04254 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX04254 NALP1 antibody.
Antigen retrieval : 10 mM citrate buffer (pH 6)
Dilution : 1:50

Anti-NALP1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04254

GTX04254 ICC/IF Image

ICC/IF analysis of SH-SY5Y cells using GTX04254 NALP1 antibody.
Dilution : 1:50
Blue : DAPI

Anti-NALP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04254

GTX04254 IHC-P Image

IHC-P analysis of human colon tissue using GTX04254 NALP1 antibody.
Antigen retrieval : 10 mM citrate buffer (pH 6)
Dilution : 1:50

REFERENCE

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REVIEW

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Package List Price ($)
$ 399