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NKX6-1 antibody [NKX61/2561]

Anti-NKX6-1 antibody [NKX61/2561] used in Protein Array (Protein Array). GTX04829
Anti-NKX6-1 antibody [NKX61/2561] used in (). GTX04829
Anti-NKX6-1 antibody [NKX61/2561] used in IHC (Paraffin sections) (IHC-P). GTX04829
Anti-NKX6-1 antibody [NKX61/2561] used in IHC (Paraffin sections) (IHC-P). GTX04829

Cat. No. GTX04829

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 NKX61/2561

Isotype

 IgG2c

Application

 IHC-P, Protein Array

Reactivity

 Human
Package
100 μg ($529)
See all NKX6-1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1- 2 μg/mL
Protein Array Assay dependent

Note :

IHC-P
Recommend using heat mediated antigen retrieval in 10mM Tris with 1mM EDTA (pH 9.0)
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human NKX6.1 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Nucleus

Background

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES

Anti-NKX6-1 antibody [NKX61/2561] used in Protein Array (Protein Array). GTX04829

GTX04829 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using NKX6-1 antibody [NKX61/2561]. Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Anti-NKX6-1 antibody [NKX61/2561] used in (). GTX04829

GTX04829 Image

SDS-PAGE analysis of GTX04829 NKX6-1 antibody [NKX61/2561].
Loading : 2 μg

Anti-NKX6-1 antibody [NKX61/2561] used in IHC (Paraffin sections) (IHC-P). GTX04829

GTX04829 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX04829 NKX6-1 antibody [NKX61/2561].

Anti-NKX6-1 antibody [NKX61/2561] used in IHC (Paraffin sections) (IHC-P). GTX04829

GTX04829 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX04829 NKX6-1 antibody [NKX61/2561].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529