GeneTex

  • Country / Location Selection

United States (US)

PCNA antibody [131-11964(19F4)]

Cat. No. GTX39739

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 131-11964(19F4)

Isotype

 IgG1

Application

 IHC

Reactivity

 Human, Rat
Package
100 μg ($399)
See all PCNA products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC Assay dependent
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

Product Note

PCNA (Proliferating Cell Nuclear Antigen), formerly called Cyclin, is a 36 kDa proliferation associatedantigen.

PROPERTIES

Form

Liquid

Buffer

10mM Phosphate, 150mM NaCl

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.20 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified Proliferating Cell Nuclear Antigen

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11163840

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

proliferating cell nuclear antigen , ATLD2

Cellular Localization

Nucleus

Background

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Application Reference

Illing RB et al. Eur J Neurosci 2019; Mitotic activity, modulation of DNA processing, and purinergic signalling in the adult rat auditory brainstem following sensory deafferentation.
Application : IHC
Reactivity : Rat
Submit a Reference

REVIEW

There are currently no reviews for PCNA antibody [131-11964(19F4)] (GTX39739). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399