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PSD95 antibody [HL2382]

Recombinant antibody Overexpression
Anti-PSD95 antibody [HL2382] used in Western Blot (WB). GTX638590
Anti-PSD95 antibody [HL2382] used in Western Blot (WB). GTX638590
Anti-PSD95 antibody [HL2382] used in Western Blot (WB). GTX638590

Cat. No. GTX638590

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL2382

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all PSD95 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:10000
Not tested in other applications.

Calculated MW

80 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No Preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Synthetic peptide of mouse PSD95.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

discs large MAGUK scaffold protein 4 , Dlgh4 , PSD-95 , PSD95 , SAP90 , SAP90A

Cellular Localization

Cell membrane,Postsynaptic density,Cell junction, synapse,Cytoplasm,Cell projection, axon

Background

Enables ionotropic glutamate receptor binding activity and scaffold protein binding activity. Involved in several processes, including dendritic spine morphogenesis; locomotory exploration behavior; and neurotransmitter receptor localization to postsynaptic specialization membrane. Acts upstream of or within protein localization to synapse; regulation of long-term neuronal synaptic plasticity; and synaptic vesicle maturation. Located in several cellular components, including axon; postsynaptic density membrane; and synaptic vesicle. Is extrinsic component of cytoplasmic side of plasma membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Colocalizes with postsynaptic membrane. Is expressed in central nervous system; dorsal root ganglion; olfactory epithelium; and retina. Used to study Williams-Beuren syndrome and autism spectrum disorder. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human DLG4 (discs large MAGUK scaffold protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Database

Research Area

DATA IMAGES

Anti-PSD95 antibody [HL2382] used in Western Blot (WB). GTX638590

GTX638590 WB Image

Various tissue extracts (50 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PSD95 antibody [HL2382] (GTX638590) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-PSD95 antibody [HL2382] used in Western Blot (WB). GTX638590

GTX638590 WB Image

Rat tissue extract (50 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with PSD95 antibody [HL2382] (GTX638590) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-PSD95 antibody [HL2382] used in Western Blot (WB). GTX638590

GTX638590 WB Image

Overexpression

Non-transfected (–) and transfected (+) 293T whole cell extracts (5 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PSD95 antibody [HL2382] (GTX638590) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
$ 169
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