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QDPR antibody

Anti-QDPR antibody used in Western Blot (WB). GTX104428
Anti-QDPR antibody used in Western Blot (WB). GTX104428
Anti-QDPR antibody used in IHC (Paraffin sections) (IHC-P). GTX104428

Cat. No. GTX104428

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse
Package
100 μl ($399),
25 μl ($169)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

Positive Control

Jurkat , Mouse liver

Predict Reactivity

Rat, Rabbit, Bovine, Chicken, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.92 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human QDPR. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11165096

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

quinoid dihydropteridine reductase , DHPR , HDHPR , PKU2 , SDR33C1

Background

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-QDPR antibody used in Western Blot (WB). GTX104428

GTX104428 WB Image

Sample (30 ug of whole cell lysate)
A: Jurkat
12% SDS PAGE
GTX104428 diluted at 1:1000

Anti-QDPR antibody used in Western Blot (WB). GTX104428

GTX104428 WB Image

Sample (50 ug of whole cell lysate)
A: mouse Liver
12% SDS PAGE
GTX104428 diluted at 1:1000

Anti-QDPR antibody used in IHC (Paraffin sections) (IHC-P). GTX104428

GTX104428 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using QDPR(GTX104428) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169