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TMPRSS2 antibody, Internal

Anti-TMPRSS2 antibody, Internal used in Western Blot (WB). GTX88625
Anti-TMPRSS2 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX88625

Cat. No. GTX88625

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all TMPRSS2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.3μg/ml
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88625-PEP).

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-TDWIYRQMRADG, from the internal region of the protein sequence according to NP_005647.2.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transmembrane serine protease 2 , PP9284 , PRSS10

Cellular Localization

Cell membrane

Background

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Database

Research Area

DATA IMAGES

Anti-TMPRSS2 antibody, Internal used in Western Blot (WB). GTX88625

GTX88625 WB Image

WB analysis of human pancreas and kidney lysates (35μg protein in RIPA buffer) using GTX88625 TMPRSS2 antibody, Internal.
Dilution : 0.5μg/ml

Dilution : 0.5μg/ml

Anti-TMPRSS2 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX88625

GTX88625 IHC-P Image

IHC-P analysis of human kidney tissue using GTX88625 TMPRSS2 antibody, Internal.
Antigen retrieval : Heat induced antigen retrieval with citrate buffer pH 6
Dilution : 8μg/ml

Antigen retrieval : Heat induced antigen retrieval with citrate buffer pH 6
Dilution : 8μg/ml

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399