APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 μg/mL |
5 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
HEK293 Cell Slide(GTX25524) , HEK293 Cell Lysate(GTX27902)
Product Note
WDR5 antibody is human specific. WDR5 antibody is predicted to not cross-react with other WDR family members.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
WDR5 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human WDR5.The immunogen is located within the first 50 amino acids of WDR5.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
WD repeat domain 5 , BIG-3 , CFAP89 , SWD3
Cellular Localization
Nucleus
Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX17169 WB Image
WB analysis of 293 cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX17169 WDR5 antibody. Working concentration : 1 μg/ml
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GTX17169 ICC/IF Image
ICC/IF analysis of 293 cells using GTX17169 WDR5 antibody. Working concentration : 20 μg/ml
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GTX17169 ICC/IF Image
ICC/IF analysis of 293 cells using GTX17169 WDR5 antibody. Working concentration : 5 μg/ml
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REFERENCE
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REVIEW
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