APPLICATION
Product Note
The peptide was used in the production of GTX89716.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Region/Sequence
C-TVKWYQLTAATYL
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha , Cpk , Pi3-K-C2(Alpha) , Pi3-K-C2A , Pi3K-C2-Alpha , Pi3K-C2Alpha , Pik3C2A
Background
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]
Research Area
REFERENCE
There are currently no references for PI3 kinase C2 alpha blocking peptide (GTX89716-PEP). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PI3 kinase C2 alpha blocking peptide (GTX89716-PEP). Be the first to share your experience with this product.