APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:100~1:500 |
1:50~1:100 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human Heparin Cofactor II (41-90).
Purification
Purified by antigen-affinity chromatography
From serum
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
D22S673 , HC2 , HCF2 , HCII , HLS2 , LS2 , SERPIND1 , THPH10 , serpin family D member 1 , Heparin Cofactor II , serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Background
This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015]
Database
Research Area
DATA IMAGES
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GTX87285 ICC/IF Image
ICC/IF analysis of HepG2 cells using GTX87285 Heparin Cofactor II antibody. The picture on the right is blocked with the synthesized peptide.
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GTX87285 IHC-P Image
IHC-P analysis of human liver carcinoma tissue using GTX87285 Heparin Cofactor II antibody. The picture on the right is blocked with the synthesized peptide.
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REFERENCE
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REVIEW
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