CD3 epsilon antibody [145-2C11]Cat No. GTX14351
Host :
Armenian Hamster
Clonality :
Monoclonal
Application :
WB, ICC/IF, IHC-Fr, FACS, IP, Activation, Depletion, Neutralizing/Inhibition
Reactivity :
Ms
Product Note :
The complete 145-2C11 antibody is commonly used to stimulate T cells in vitro however, when used in vivo activation of resting T cells results in cytokine release and toxicity caused by Ab-mediated cross-linking of T cells and Fcγ receptor-bearing cells. To avoid these complications non-Fc receptor binding F(ab’)2 fragments of the 145-2C11 antibody are commonly used. This non-FcR-binding anti-CD3 induces apoptosis of Ag-activated T cells in vivo by allowing durable expression of the TCR and sustained signaling. Foxp3+ Tregs have been shown to be resistant to CD3 antibody-mediated depletion.
Package :
500 μg
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IL2 Receptor alpha antibody [PC61.5]Cat No. GTX01472
Host :
Rat
Clonality :
Monoclonal
Application :
IHC-Fr, FACS, IP, Depletion
Reactivity :
Ms
Package :
100 μg
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HLA-DPA1 antibodyCat No. GTX104414
Host :
Rabbit
Clonality :
Polyclonal
Application :
WB, ICC/IF, IHC-P, IHC-Fr
Reactivity :
Hu, Ms
Package :
100 μl, 25 μl
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Calcineurin B antibodyCat No. GTX109127
Host :
Rabbit
Clonality :
Polyclonal
Application :
WB, IHC-P
Reactivity :
Hu, Ms, Rat, Zfsh
Package :
100 μl, 25 μl
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Fc epsilon R1 alpha antibodyCat No. GTX04729
Host :
Rabbit
Clonality :
Polyclonal
Application :
WB, ICC/IF, IHC-P
Reactivity :
Hu, Ms, Rat
Package :
100 μl
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CD3 antibody [OKT3] (PerCP-Cy5.5)Cat No. GTX79906-11
Host :
Mouse
Clonality :
Monoclonal
Application :
FACS
Reactivity :
Hu, Chmp
Product Note :
This antibody recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia.
Package :
100 test
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CD2 antibody [N1C1]Cat No. GTX101874
Host :
Rabbit
Clonality :
Polyclonal
Application :
WB, IP
Reactivity :
Hu
Product Note :
IP/MS validation was supported by references (PMID:30377379)
Package :
100 μl, 25 μl
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ZAP70 (phospho Tyr319) / Syk (phospho Tyr352) antibody [GT364]Cat No. GTX634476
Host :
Mouse
Clonality :
Monoclonal
Application :
WB
Reactivity :
Hu, Ms
Package :
100 μl, 25 μl
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CD3 antibody [OKT3] (PE)Cat No. GTX79906-08
Host :
Mouse
Clonality :
Monoclonal
Application :
FACS
Reactivity :
Hu, Chmp
Product Note :
This antibody recognizes the CD3 antigen of the TCR/CD3 complex on mature human T cells. This antibody, also known as Orthoclone OKT3 or Muromonab-CD3, has been extensively used as a drug for therapy of acute, glucocorticoid resistant rejection of allogenic renal, heart and liver transplants. It has also been investigated for use in treating T-cell acute lymphoblastic leukemia.
Package :
100 test
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IL3 Receptor beta antibody [1D5E4]Cat No. GTX04642
Host :
Mouse
Clonality :
Monoclonal
Application :
WB, IHC-P, FACS, ELISA
Reactivity :
Hu, Ms, Rat
Package :
100 μl
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