Form
Liquid
Buffer
PBS, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human ARFGEF2 (1491-1540).
Purification
Purified by antigen-affinity chromatography
From serum
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Synonyms
ADP ribosylation factor guanine nucleotide exchange factor 2 , ARFGEF2 , BIG2 , PVNH2 , dJ1164I10.1
Cellular Localization
Cytoplasm,Membrane,Golgi apparatus,Cytoplasm,Perinuclear region,Golgi apparatus,trans-Golgi network,Endosome,Cytoplasm,Cytoskeleton,Microtubule organizing center,Centrosome,Cell projection,Dendrite,Cytoplasmic vesicle,Cell junction,Synapse,Cytoplasm,Cytoskeleton
Background
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Database
Research Area