Form
Liquid
Buffer
PBS, BSA
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Mouse
Immunogen
C57BL/10 mouse spleen cells enriched with T cells
Purification
Protein G affinity purified
Conjugation
Phycoerythrin (PE)
RRID
AB_378547
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
Integrin Alpha M , Cd11B/Cd18 , Cr3 , Cr3A , Cd11B , F730045J24Rik , Ly-40 , Mac1 , Mac-1 , Mac-1A , Itgam
Background
Recognises the murine CD11b cell surface antigen (also known as the alpha M integrin chain), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor (3).
Research Area