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CD36 antibody [FA6.152]

Cat. No. GTX44214

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 FA6.152

Isotype

 IgG1

Application

 FACS, IHC

Reactivity

 Human
Package
100 μg ($399)
See all CD36 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 2 μg
IHC Assay dependent

Note :

FACS
5x10⁵ cells/test
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Product Note

The molecular weight of the recognized antigen is 90 kDa. Recognizes the glycoprotein gp lllbcorresponding to the thrombospondin receptor. This antibody agglutinates fetal but not adult erythrocytes. Itdoes not react with lymphocytes and granulocytes. It reacts both with fetal and adult monocytes,megakaryocytes, platelets and reticulocytes. The thrombospondin receptor is a very early marker oferythroid differentiation.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.20 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

20 week-old human fetal red blood cells.

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_11165682

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD36 molecule , BDPLT10 , CHDS7 , FAT , GP3B , GP4 , GPIV , PASIV , SCARB3

Cellular Localization

Cell membrane , Golgi apparatus , Apical cell membrane

Background

The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]

Database

Research Area

REFERENCE

Application Reference

Latorre D et al. Toxins (Basel) 2015; 7 (12) : 5472-83 Bovine Lactoferrin-Induced CCL1 Expression Involves Distinct Receptors in Monocyte-Derived Dendritic Cells and Their Monocyte Precursors.
Reactivity : Human

Clone Reference

Prignano F et al. Int J Dermatol 2012; 51 (5):564-7 Why is Kikuchi-Fujimoto disease misleading?
Application : IHC
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Package List Price ($)
$ 399