APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:100-1:200 |
Note :
IHC-P
Heat-induced epitope retrieval (HIER) at pH 9 for 10 - 30 minutes
|
Not tested in other applications.
Calculated MW
Positive Control
Lung, Muscle
PROPERTIES
Form
Liquid
Buffer
Tris, 1% BSA
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human Placenta protein.
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Collagen Type Iv Alpha 1 Chain , Bsvd , Rator , Col4A1
Background
This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Research Area
DATA IMAGES
|
GTX57183 IHC-P Image
IHC-P analysis of human liver tissue using GTX57183 COL4A1 antibody [IHC549]
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REFERENCE
There are currently no references for COL4A1 antibody [IHC549] (GTX57183). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for COL4A1 antibody [IHC549] (GTX57183). Be the first to share your experience with this product.