APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 μg/mL |
2 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Mouse Heart Tissue Lysate(GTX27932)
Product Note
Multiple isoforms of CTRP3 are known to exist. CTRP3 antibody is predicted to not recognize other members of the CTRP protein family.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
CTRP3 antibody was raised against a 16 amino acid synthetic peptide from near the center of human CTRP3.The immunogen is located within the first 50 amino acids of CTRP3.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C1q and TNF related 3 , C1ATNF3 , CORCS , CORS , CORS-26 , CORS26 , CTRP3
Cellular Localization
Secreted
Background
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-?-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development (5).
Database
Research Area
DATA IMAGES
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GTX85505 WB Image
WB analysis of mouse heart cell lysate in (A) absence and (B) presence of blocking peptide. using GTX85505 CTRP3 antibody. Working concentration : 1 μg/ml
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GTX85505 IHC-P Image
IHC-P analysis of mouse heart tissue using GTX85505 CTRP3 antibody. Working concentration : 10 μg/ml
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GTX85505 IHC-P Image
IHC-P analysis of mouse heart tissue using GTX85505 CTRP3 antibody. Working concentration : 2 μg/ml
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REFERENCE
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REVIEW
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