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Integrin alpha 9 + beta 1 antibody [Y9A2] (Azide free)

Cat. No. GTX39988

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 Y9A2

Isotype

 IgG1

Application

 FACS, IP, Neutralizing/Inhibition

Reactivity

 Human, Guinea pig
Package
50 μg ($479)
See all Integrin alpha 9 + beta 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
IP Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

Neutralizing/Inhibition
In functional applications Mouse anti Human Integrin alpha 9 beta 1 antibody, clone Y9A2 has been shown to cause 100% inhibition of α9β1-mediated adhesion to the third fibronectin type III repeat in tenascin at <10ug/ml. Mouse anti Human Integrin alpha 9 beta 1 antibody, clone Y9A2 has been used to demonstrate Itgα9 blocking of progenitor cell proliferation (Schreiber et al. 2009).
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Murine L cells transfected with human alpha-9 integrin.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

RLC Antibody , ALPHA-RLC Antibody , ITGA9 Antibody , ITGA4L Antibody

Background

This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 479
Custom Conjugations