KLRC1 antibody

Cat. No. GTX04877

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF
Reactivity	Human
Package	400 μl ($399)

See all KLRC1 products

Datasheet

View product citations for antibody GTX04877 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:1000
ICC/IF	1:10-1:50

Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KLRC1.

Purification

Purified by Protein A followed by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD159A,KLRC1,NKG2,NKG2A,killer cell lectin like receptor C1

Cellular Localization

Membrane

Background

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015]

Database

Gene ID: 3821 KLRC1
UniProt: P26715 KLRC1

Research Area

DATA IMAGES

GTX04877 WB Image

WB analysis of MDA-MB-435 whole cell lysate using GTX04877 KLRC1 antibody.
Loading : 35 μg

GTX04877 ICC/IF Image

ICC/IF analysis of MDA-MB-435 cells using GTX04877 KLRC1 antibody.
Green : Primary antibody
Red : Actin
Blue : DAPI

REFERENCE

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REVIEW

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Package

List Price ($)

400 μl

$ 399

Qty