APPLICATION
Product Note
The peptide was used in the production of GTX89763.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Region/Sequence
CNCGAKRCRRFLN
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Lysine Methyltransferase 2B , Cxxc10 , Dyt28 , Hrx2 , Mll1B , Mll2 , Mll4 , Trx2 , Wbp-7 , Wbp7 , Kmt2B
Background
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
Research Area
REFERENCE
There are currently no references for MLL4 blocking peptide (GTX89763-PEP). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for MLL4 blocking peptide (GTX89763-PEP). Be the first to share your experience with this product.