APPLICATION
Application Note
Recommended starting dilutions: For IHC/IF: Use at 1:1000 - 1:2000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Calculated MW
Product Note
proteolipid protein 1
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
100 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptides
Purification
Affinity purified antibody
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
proteolipid protein 1 , GPM6C , HLD1 , MMPL , PLP , PLP/DM20 , PMD , SPG2
Cellular Localization
Cell membrane
Background
This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015]
Database
Research Area
DATA IMAGES
|
GTX85465 IHC Image
In this tissue section through an e13 mouse brain, PLP (green staining) can be seen in immature oligodendrocytes of white matter tracts. DAPI (blue staining) allows visualization of nuclei.
|
REFERENCE
There are currently no references for Myelin PLP antibody (GTX85465). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Myelin PLP antibody (GTX85465). Be the first to share your experience with this product.