APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:100~1:500 |
1:50~1:100 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human STEAP2 (431-480).
Purification
Purified by antigen-affinity chromatography
From serum
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
IPCA1 , PCANAP1 , PUMPCn , STAMP1 , STEAP2 , STEAP2 metalloreductase , STMP
Cellular Localization
Endosome membrane,Cell membrane
Background
This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Database
DATA IMAGES
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GTX87297 ICC/IF Image
ICC/IF analysis of A549 cells using GTX87297 STEAP2 antibody. The picture on the right is blocked with the synthesized peptide.
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GTX87297 IHC-P Image
IHC-P analysis of human colon carcinoma tissue using GTX87297 STEAP2 antibody. The picture on the right is blocked with the synthesized peptide.
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REFERENCE
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REVIEW
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