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Steroidogenic Factor 1 antibody [N1665]

Cat. No. GTX01827

Reference 5

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 N1665

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($599)
See all Steroidogenic Factor 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50-1:100

Note :

IHC-P
Pretreatment of deparaffinized tissue with heat-induced epitope retrieval or enzymatic retrieval is recommended.
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

Positive Control

Adrenal cortical carcinoma

PROPERTIES

Form

Liquid

Buffer

Tris-HCl, 0.2% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthesized peptide corresponding to amino acids 220-461 of human SF-1 protein

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

nuclear receptor subfamily 5 group A member 1 , AD4BP , ELP , FTZ1 , FTZF1 , POF7 , SF-1 , SF1 , SPGF8 , SRXX4 , SRXY3 , hSF-1

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Clone Reference

2020; The Leydig cell tumor Scaled Score (LeSS) A method to distinguish benign from malignant cases, with additional correlation with MDM2 and CDK4 amplification
Application : IHC-P
Reactivity : Human
2020; Digital analysis of hormonal immunostaining in pituitary adenomas classified according to WHO 2017 criteria and correlation with preoperative laboratory findings
Reactivity : Human
2020; A Morphologic and Immunohistochemical Comparison of Nuclear β-Catenin Expressing Testicular Sertoli Cell Tumors and Pancreatic Solid Pseudopapillary Neoplasms Supporting Their Continued Separate Classification
2019; A Novel Dual Immunostain to Characterize Sloughed Cells in Testicular Biopsies for Infertility
Reactivity : Human
2019; Hypothalamic Vasopressin-Producing Tumors: Often Inappropriate Diuresis But Occasionally Cushing Disease
Reactivity : Human
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REVIEW

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Package List Price ($)
$ 599